2306/JN - Chromatography System for Protein and Nucleic Acid Purification

The Bose Lab works on understanding the function of non-coding RNA: protein complexes, and how they regulate gene expression. The group uses a combination of functional genomics, biochemistry and structural biology to probe the mechanism of protein:RNA complexes. The lab is generously funded by a Sir Henry Dale Fellowship from the Wellcome Trust and the Royal Society. The group is also associated with a wider cross-faculty and departmental grouping of labs focused on nucleic acids research within the University of Sheffield as part of the Sheffield Institute for Nucleic Acids; the equipment will therefore be of wider interest to a number of groups within the University. Our work studies …

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