GB-Salisbury: Pharma in vitro metabolism

NOTE: This notice was updated on 28 August 2016 for the following reason: Description of requirements changed to the following and requirement to be GLP compliant now removed as a pre-requisite to submitting an Expression of Interest Dstl is developing a number of active pharmaceutical ingredients (API) as medical countermeasures. In vitro metabolism studies of three API are required as the project moves forwards. These include determination of metabolism kinetics, metabolite identification, metabolising enzyme identification, blood:plasma ratio determination and identification of efflux transporters. All requirements will need suitably qualified analytical chemistry methods to quantify t…

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