INRA BCG Challenge

This project builds and extends on significant progress made over the last decade in the development of TB vaccines for cattle and addresses key policy requirements that arise from the short duration of immunity induced in cattle by BCG. First, APHA will determine whether annual revaccination of cattle with BCG can maintain sufficient levels of protection over time. APHA will also test if re-vaccination with BCG results in re-sensitisation of vaccinated animals to the tuberculin skin test and whether the DIVA test can still be used in the face of a number of rounds of BCG vaccination and tuberculin skin testing. APHAwill also investigate whether novel vaccination regimes can be developed…

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