Provision of Mycobacterial Determinants of Survival and Fitness within the Bovine Host
What the buyer wrote
AIMS: The overall goal of this proposal is to use to Transposon Directed Insertion Sequencing (TraDIS) methodology to determine M. bovis gene fitness and essentiality in disease relevant models of natural infection. This approach will result in (a) identification of the metabolic and physiological adaptations that M. bovis makes in the bovine host (b) identification of the selective pressures within bovine alveolar macrophages and the bovine host (c) a list of attenuating mutations that will allow us in future projects to rationally design novel and improved vaccines for BTB (d) a saturated transposon library of M. bovis and an essentiality dataset for distribution and use by the mycoba…
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Details
- What the buyer calls it
- Provision of Mycobacterial Determinants of Survival and Fitness within the Bovine Host
- How they are buying
- The buyer did not say
- Type
- services
- Suitable for small firms
- The buyer says yes. What that is worth
- Work starts
- 31 Mar 2016
- Work ends
- 31 Mar 2020
Who the buyer named
Emma Roberts was the named contact on this notice.